Regulatory tracker

The Drug Enforcement Administration (DEA) is revoking the exempted status for certain nonnarcotic prescription products that are currently on DEA's Table of Exempted Prescription Products, but whose National Drug Codes (NDC) are inactive because they are no longer available and/o

On August 12, 2026, the Drug Enforcement Administration (DEA) published a temporary order placing O-desmethyltramadol (other names: O-DSMT; desmetramadol; 3-[(1R,2R)-2-[(dimethylamino)methyl]-1- hydroxycyclohexyl]phenol), including its salts, isomers, and salts of isomers wheneve

Marital Transgression, Marital Relationship, Forgiveness, Depression, Anxiety, Stress, Ruminations — Islamic Integrated Forgiveness Therapy (IIFT), Enright's Forgiveness Therapy (EFT)

Depression, Anxiety, Trauma Patients — D-Cycloserine (DCS), Transcranial Magnetic Stimulation, Unified Protocol

General Mental Health and Well-Being, Mental Disorders, Common Mental Disorders (CMD) — Digital wellbeing promoting intervention with the BitHabit app

Caregiver Burden, Caregiver Burnout, Caregiver Anxiety, Alzheimer Disease Dementia — Peer Support, Usual Care

Traumatic Brain Injuries — Therapeutic Benefits of Pareidolia, Active Comparator #1

Anxiety, Depression - Major Depressive Disorder, Burnout, Insomnia, Resilience, Feasibility, Acceptability — Transcendental Meditation

Health Anxiety — THIS WAY UP iCBT, 90SecondHealth Anxiety

End-Stage Kidney Disease (ESKD) — virtual reality-guided imagery (VRGI)

Chronic Musculoskeletal Pain, Sexual Assault, Posttraumatic Stress Disorder (PTSD) — 17β-estradiol, Placebo

Posttraumatic Stress Symptoms, Heavy Alcoholic Consumption, Alcohol Use Disorder (AUD) — Transcutaneous auricular neurostimulation (tAN), Active Sham

Schizophrenia; Psychosis — Group Therapy, Treatment as Usual (TAU)

LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction — Adapted Lakota Family Acceptance Program

Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety, Depression — Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation

Postpartum Depression (PPD), Postpartum Anxiety

Hemodialysis — Combined Aerobic and Resistance Exercise, Combined Aerobic and Resistance Exercise, Combined Aerobic and Resistance Exercise

Post-traumatic Stress Symptoms, Anxiety, Depression Disorder, Gastrointestinal Disease — PREPARE-GI

Mental Disorders, Mood Disorders, Anxiety Disorders, Generalized Anxiety Disorder — Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty (CBT-IU), Group Transdiagnostic Applied Relaxation (AR)

Virtual Reality — ReviMed group, Control Group (A):

Alexithymia, Anxiety, Interpersonal Problems, Emotion Regulation — DBT-based Group Skills Training (DBT-GST), CBT-based Group Skills Training (CBT-GST)

Implementation Science, Chronic Disease Self-management, Mental Illness, Addiction, Primary Care Patients With Chronic Conditions — The Chronic Disease Self-Management Program (CDSMP), Treatment as Usual plus self-management information

Knowledge Gaps, Attitudes, Stigma of Mental Illness, Help-seeking Intention — Culturally sensitive addiction psychoeducation program, Secular

Schizophrenia and Other Psychotic Disorders, Healthy Adult — Methylene Blue

Premenstrual Dysphoric Disorder (PMDD)

Suicidal Ideation, Mental Health, Depression, Geriatric Psychiatry, Aging — Gamified VR-Based Exercise Program, Conventional Exercise Program

Anxiety, Depression, Mental Health, Psychiatric Inpatients — High-Intensity Interval Training (1 × 4)

Post-Traumatic Stress Disorder, Chronic, Depressed Mood, Depressive and Anxiety Disorders, Anxiety, Depression - Major Depressive Disorder — Cognitive Processing Therapy

Major Depressive Disorder (MDD), Treatment Resistant Depression, Major Depression — MagVenture TMS Therapy System with Localite Navigation System and actiCHamp EEG

Anxiety, Cervical Cancer Screening, Health Education, Wellbeing — cervical cancer Awareness education to aid Confidence and screening upTake (ACT), Control group

Virtual Reality — Experimental

Dental Anxiety, Dental Anxiety in Children, Preoperative Anxiety — Virtual Reality Storytelling, Traditional Storybook Reading

Posttraumatic Stress Disorder, Metabolic Syndrome, Insulin Resistance — prazosin

Complex Post-Traumatic Stress Disorder (CPTSD) — Prolonged Exposure, EMDR, ESTAIR

Gambling Disorder, Gambling — Digital Cognitive Behavioral Therapy for Gambling Disorder, Digital Family Intervention for Gambling-Related Harms, Face-to-Face Cognitive Behavioral Therapy for Gambling Disorder

The Food and Drug Administration (FDA or the Agency) is describing the approaches it is considering for the design of early- phase clinical trials of ibogaine drug products and is opening a public docket to receive comments. The Department of Health and Human Services (HHS) is fu

Cancer — IHSAN Model-based Islamic Spiritual Care, CBT-based Psychological Support

Bipolar Disorder (BPD) — Bright Light Therapy, Placebo Light Therapy

Anorexia Nervosa, Attentional Bias, Psychophysiology, Food, Interoception, Anxiety — Attentional Bias Modification Training

Emotion Journal, Pediatric Intensive Care, Emotion Regulation, Emotional Awareness — Emotion Diary Administration

Test Anxiety, Test Anxiety Scale, Exam Anxiety — Neurofeedback Therapy, Cognitive Behavioural Therapy-based Psychoeducation

Preoperative Anxiety, Laparoscopic Cholecystectomy — Humor-Based Video Intervention, Routine Preoperative Care and Education

Coronary Angiography (CAG) — Virtual Reality Application

Wellbeing, Social Isolation in Older Adults, Social Prescribing, Anxiety Depression, Quality of Life (QOL) — Music / Visual Arts

Major Depressive Disorder (MDD — Brief Psychoanalytic Therapy, Cognitive Behavioral Therapy

Psychological Well-being, Gratitude, Hope, Spirituality, Stress, Anxiety, Depression — Examen Meditation

Major Depressive Episode (MDE), Unipolar Disorder, Bipolar 1 Disorder — Stimulation by the Sigma ECT/FEAST device, Stimulation by Sigmastim ECT 200J device administered in right unilateral (RUL), Stimulation by Sigmastim ECT 200J device administered in bilateral (BT)

Bipolar Disorder in Remission, Major Depression in Remission

Weight Regain After Bariatric Surgery and Food Addiction, Eating Behavior, Body Image — Intuitive Eating Intervention, Standard Nutritional Counseling

Well Being, Drug Addiction, Tobacco Use, Alcohol Abuse, Life Skills, Violence, Bullying, Health Literacy — life skills primary prevention

Schizophrenia, Bipolar Affective Disorder — Quetiapine (drug), quetiapine + aripiprazole, quetiapine + haloperidol

Health College Students — Virtual Reality-Assisted Tai Chi Training

Burn Patients, Psychosocial, Body Image, Self Esteem, Anxiety, Depression — Psychosocial Intervention

Addictive Behaviors, Internet Addiction Disorder, Gambling, Technology Addiction, Food Addiction, Compulsive Sexual Behavior, Screen Use — Questionnaires, Telephone interview

Schizophrenia, Auditory Verbal Hallucinations — Neuronavigated repetitive transcranial magnetic stimulation (rTMS), Sham repetitive transcranial magnetic stimulation (rTMS)

Healthy Control Subjects, Schizophrenia Diagnosis

SCHIZOPHRENIA 1 (Disorder), Schizoaffective Disorder, Healthy Adult Participants — Motion Perception Task, Sine Wave Speech Task, Volatility Task

Cryoneurolysis, Bipolar Radiofrequency Ablation, Genicular Nerves, Pain Relief, Symptomatic, Knee Osteoarthritis — Ultrasound-guided cryoneurolysis, Bipolar radiofrequency ablation

This document corrects technical errors in the final action that appeared in the July 31, 2026 Federal Register titled "Medicare Program; FY 2027 Inpatient Psychiatric Facilities Prospective Payment System--Rate Update".

This proposed rule would amend the regulations of the Drug Enforcement Administration (DEA) to extend the time allowed for reexports of controlled substances outside of the European Economic Area from 180 days from the date of original release from U.S. Customs and Border Protect

PTSD - Post Traumatic Stress Disorder, Trauma-related Nightmares — CAUD-PIN (CAUchemar Detection on INdividualized Parameters) - AI-based predictive algorithm forTrauma-related nightmare awakenings

Post Traumatic Stress Disorder

Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms — Hyperbaric Oxygen Therapy (HBOT)

Substance-Related Disorders, Substance Use Disorder, Sleep Wake Disorders, Cognitive Dysfunction

Substance-related Disorders, Mental Health Literacy, Adolescent Health, Substance Use Disorder (SUD) — Brave Heart Intervention

Nicotine Dependence — Psilocybin (drug)

Major Depression — iTBS, rTMS

Schizo-affective Disorder, Non Organic Psychosis, Schizophenia Disorder — Positive Emotion Program for Schizophrenia (PEPS), a psychotherapeutic intervention,

Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 — Abiraterone Acetate, Biospecimen Collection, Bone Scan

Acute Stress Disorder, Post Traumatic Stress Disorder PTSD — Defusing, Psychological First Aid (PFA)

Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms, PTSD — Hyperbaric Oxygen Therapy (HBOT)

Methamphetamine Use Disorder, Pregnancy — 4- Week Dual-Target Transcranial Magnetic Stimulation (TMS), Accelerated Dual-Target Transcranial Magnetic Stimulation (aTMS), Treatment as Usual (TAU)

SCHIZOPHRENIA 1 (Disorder) — DSP-2342

Parasite and Infestation Physician-Patient Diagnostic Incongruency — No intervention - observational study

Substance Abuse, Opioid Abuse (Disorder), Overdose Prevention, Substance Use Disorder (SUD), Adolescent Substance Use, Rural Health — Navigator - Flexible Care Management

Depressive Disorder, Treatment-Resistant — Short-Term Dynamic Psychotherapy, Mindfulness-Based Cognitive Therapy

Irvine Labs, Inc. has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Cargill, Incorporated has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Benuvia Operations, LLC. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship, Parent-Child Relationship, Parent-Child Relations, Stress Disorder, Post Traumatic, PTSD, Parenting, Child Behavior, Emotional Regulation, Emotion Regulation — Parenting-STAIR Modular (PSTAIR-M), Tr

Internet Gaming Disorder — "Activate Neural Circuits + Promote Social Rewards" Dual-target Neurofeedback Training, "Activate Only the Neural Circuits" Neurofeedback Training, Sham Feedback

Psychiatric Disorders — person-centred interventions

Alcohol Use Disorder — Thiamine

Substance Use (Drugs, Alcohol), Tobacco Use, Adolescent Substance Use — Integrated Community Engagement Collaborative, School-Based Data Collection and Reporting without Network Coordinator Support

Dysfunctional Breathing, Physical Activity, Nicotine Dependence — Observational evaluation.

Treatment Resistant Depression (TRD) — Dehydroepiandrosterone (DHEA), Placebo

Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide, Suicidal Ideation, Mental Disorders — Soterix 1x1 tES mini-CT

The Food and Drug Administration (FDA or the Agency) is issuing an order under the Federal Food, Drug, and Cosmetic Act (FD&C Act) debarring Jeffrey Thies for a period of 10 years from importing or offering for import any drug into the United States. FDA bases this order on a fin

Posttraumatic Stress Disorder (PTSD), Posttraumatic Stress Symptom — Deep Brain Reorienting, Treatment as Usual (TAU)

Opioid Use Disorder, Major Depressive Disorder (MDD) — Transcranial Magnetic Stimulation (TMS), Sham Transcranial Magnetic Stimulation (TMS)

Alcohol Use Disorder (AUD), Suicidal Ideation — CBT4CBT

Schizophenia Disorder — WAS123, Aripiprazole (Fixed dose)

Schizophrenia Spectrum Disorders (SSD) — SELF-7, F-ACT

Cayman Chemical Company has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Eli-Elsohly Laboratories has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

Fisher Clinical Services, Inc. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Cambridge Isotope Laboratories, Inc. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Cambridge Isotope Laboratories, Inc. has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

Post-Traumatic Stress Disorder F03.950.750.500 D013313 — Art-therapy Remote Treatment for Veterans Experiencing Trauma

Opioid Use Disorder — Bup-MBC

Psoriasis Vulgaris — Oral Cannabis Extract, Topical cannabis cream

ADHD, Cannabis Use Disorder — Delayed-release, extended-release methylphenidate, Placebo

The Food and Drug Administration (FDA or the Agency) is issuing an order under the Federal Food, Drug, and Cosmetic Act (FD&C Act) debarring Sanjay Kumar for a period of 5 years from importing or offering for import any drug into the United States. FDA bases this order on a findi

The Drug Enforcement Administration proposes placing five tryptamine hallucinogens, 4-hydroxy-N,N-diisopropyltryptamine (other names: 4-OH-DiPT; 3-(2-(diisopropylamino)ethyl)-1H-indol-4- ol), 5-methoxy-alpha-methyltryptamine (other names: 5-MeO-AMT; 1-(5- methoxy-1H-indol-3-yl)pr

Post Traumatic Stress Disorder — TSND-201, Placebo

Tobacco Use Disorder/Cigarette Smoking, HIV — nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster

Eating Disorders, Substance Use — digital web based toolkit

Schizophrenia, Caregiver Burden, Quality of Life

Psychotic Disorders — Inpatient Care in a Closed Unit Incorporating Soteria Elements, Conventional Closed Psychiatric Inpatient Care

Treatment Resistant Depression (TRD), Major Depressive Disorder (MDD) — Spaced Transcranial Direct Current Stimulation (tDCS), Sham Spaced tDCS

Early Psychosis, Psychosis, Schizophrenia, Bipolar Disorder With Psychosis, Schizoaffective Disorder

Bipolar Disorder (BD) — Lurasidone

Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease, Mood Disorders, Depression, Anxiety Disorder, Bipolar Disorder, Behavior Disorders

With the issuance of this final rule, the Drug Enforcement Administration places the substance diphenidine (1-(1,2- diphenylethyl)piperidine), including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible, in sc

Post-Traumatic Stress Disorder (PTSD), Depression, Substance Use Disorder, Traumatic Injury — Trauma Resilience and Recovery Program Portal 2.0 (TRRP 2.0)

Food Addiction, Sexual Addiction — blood sampling

Addiction Disorders — attachment-focused therapeutic program, psychoeducation-based intervention (standard care)

Childbirth-related Post-traumatic Stress Disorder — City Birth Trauma Scale and Questionnaire on the assessment of healthcare utilization

Alcohol Use Disorder (AUD), Healthy Controls Group - Age and Sex-matched — [F-18]BCPP-EF, [F-18]FDG

Methamphetamine Use Disorder — Tirzepatide, Placebo (saline)

Alcohol Use Disorder (AUD), Alcohol Related Liver Disease — Endurance Exercise

Treatment Resistant Depression (TRD) — Psychedelic framing, Biomedical framing

Post-Traumatic Stress Disorder, Psychological Trauma — trauma-informed care training

Substance-related Disorders, Behavior, Addictive, Artificial Intelligence (AI) — Questionnaire assessment

Social Media Addiction — 4-STEP-TPS

Social Media Addiction — 4-STEP-TPS

Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature, Psychosis, SCHIZOPHRENIA 1 (Disorder), Schizophreni-form Disorder

Traumatic Injury, Posttraumatic Stress Disorder, Depression, Social Determinants of Health — CHW support

Anxiety, Depression Disorder, Bullying, Addiction, Suicide, Self Harm, Psychosis, Eating Disorders — program for the detection, referral, and psychoeducation in adolescents

Schizophrenia / Schizoaffective Disorder — Transcranial Alternating Current Stimulation (tACS), Sham Transcranial Alternating Current Stimulation (tACS)

Treatment Resistant Schizophrenia, Obesity & Overweight, Abdominal Obesity — The Nitraria retusa arm