Tracker · 137 filings · 14 today

Regulatory tracker

Daily aggregated filings from FDA, DEA, SEC, CMS, and the Federal Register, filtered for mental health relevance.

Latest regulatory coverage

REGULATION

Almost every branded psychiatric drug in America now sits inside a pricing deal nobody voted on

The White House added nine more drugmakers to its most-favored-nation pricing program, bringing the total to 26 companies covering an estimated 89 percent of the branded drug market. None of the new nine build their business around psychiatric drugs. That's beside the point: the company that makes esketamine signed on months ago, and the whole arrangement is voluntary, unenforced by law, and largely undisclosed to Congress.

Sep 1, 2026 · 7 min
REGULATION

Puerto Rico opens a research-policy review on psychedelics and ibogaine. It has not approved any clinical use.

Executive Order 2026-037 creates a scientific advisory committee to study whether Puerto Rico should build a pilot clinical research program for emerging therapies, including psilocybin, MDMA, and ibogaine, with veterans named as a priority population. The order explicitly does not authorize any clinical use of these compounds, a distinction worth stating plainly before the headline runs ahead of it.

Aug 5, 2026 · 8 min
REGULATION

Medicare proposes cutting physician pay for 2027. Behavioral health is one of the few specialties partly shielded from why.

CMS's newly proposed physician fee schedule cuts both Medicare conversion factors for 2027, a real, system-wide reimbursement headwind. But the same rule proposes extending Medicare's telehealth mental health flexibility through the end of 2027, and last year's most contested pay cut specifically exempted the time-based codes psychiatry and psychotherapy mostly bill under. The rule is a mixed signal, not a uniform one, and the mix matters more than the headline number.

Jul 17, 2026 · 7 min
REGULATION

DEA moves to schedule tianeptine, the other 'gas station' compound quietly building a mortality record

A federal Schedule I proposal would close the retail loophole that has let tianeptine, an atypical antidepressant abroad and an opioid-like supplement in unregulated US retail, spread through the same gas-station-and-smoke-shop channel as kratom's concentrated derivatives. It is the third distinct DEA scheduling action against this retail category in two weeks.

Jul 9, 2026 · 6 min
More regulatory coverage (2) →

Regulatory tracker

September 23, 2026
FDA
Sanjay Kumar: Final Debarment Order
scheduling

The Food and Drug Administration (FDA or the Agency) is issuing an order under the Federal Food, Drug, and Cosmetic Act (FD&C Act) debarring Sanjay Kumar for a period of 5 years from importing or offering for import any drug into the United States. FDA bases this order on a findi

View on Federal Register
DEA
Schedules of Controlled Substances: Placement of 4-Hydroxy-N,N-Diisopropyltryptamine (4-OH-DiPT), 5-Methoxy-alpha-Methyltryptamine (5-MeO-AMT), 5-Methoxy-N-Methyl-N-Isopropyltryptamine (5-MeO-MiPT), 5-Methoxy-N,N-Diethyltryptamine (5-MeO-DET), and N,N-Diisopropyltryptamine (DiPT) Into Schedule I
scheduling

The Drug Enforcement Administration proposes placing five tryptamine hallucinogens, 4-hydroxy-N,N-diisopropyltryptamine (other names: 4-OH-DiPT; 3-(2-(diisopropylamino)ethyl)-1H-indol-4- ol), 5-methoxy-alpha-methyltryptamine (other names: 5-MeO-AMT; 1-(5- methoxy-1H-indol-3-yl)pr

View on Federal Register
CT
Effect of Stellate Ganglion Block on Sleep Quality in Patients With Depression
research

Sleep and Circadian Problems — Stellate Ganglion Block

View on ClinicalTrials.gov
CT
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
research

Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development — HAP3 Family App

View on ClinicalTrials.gov
CT
Psychoeducation for Anxiety, Depression, Cognitive Avoidance, and Sense of Coherence in Women With Cancer
research

Cancer — Structured Psychoeducational Intervention

View on ClinicalTrials.gov
CT
Psychological Resilience and Quality of Life Among Caregivers of Patients With Schizophrenia
research

Schizophrenia, Caregiver Burden, Quality of Life

View on ClinicalTrials.gov
CT
Physical Activity for Depressive Symptoms in Adults With Obesity: A Randomized Controlled Feasibility Trial
research

Obesity & Overweight, Depression Disorders — Supervised Physical Activity Program

View on ClinicalTrials.gov
CT
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
research

Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being, Caregiver Burden, Caregiver Wellbeing, Mild Cognitive Impairment(MCI), Alzheimer Dementia (AD), Dementia — Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Interv

View on ClinicalTrials.gov
CT
STOP-4P for Reducing Anxiety Before Amniocentesis
research

Anxiety — STOP4P, Informational Video and Supportive Activities

View on ClinicalTrials.gov
CT
Stress-Ball Distraction for Pain and Anxiety During Painful Procedures in Critically Ill Patients
research

Procedural Pain — Stress-Ball Distraction, Standard care

View on ClinicalTrials.gov
CT
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD
research

Post Traumatic Stress Disorder — TSND-201, Placebo

View on ClinicalTrials.gov
CT
Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial
research

Tobacco Use Disorder/Cigarette Smoking, HIV — nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster

View on ClinicalTrials.gov
CT
The Interactive Media and Gender-related Stressors and Strengths Study
research

Eating Disorders, Substance Use — digital web based toolkit

View on ClinicalTrials.gov
CT
A Closed Unit Incorporating Soteria Elements Versus a Conventional Closed Psychiatric Ward
research

Psychotic Disorders — Inpatient Care in a Closed Unit Incorporating Soteria Elements, Conventional Closed Psychiatric Inpatient Care

View on ClinicalTrials.gov
September 22, 2026
CT
Cognition and Affective Research in China
research

Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease, Mood Disorders, Depression, Anxiety Disorder, Bipolar Disorder, Behavior Disorders

View on ClinicalTrials.gov
CT
ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder
psychedelics · research

Borderline Personality Disorder, Borderline Personality Pathology, Depressive Symptoms, Emotion Dysregulation, Suicidal Ideation — Psilocybin, Psilocybin-Assisted Therapy With Dialectical Behavior Therapy

View on ClinicalTrials.gov
CT
Efficacy of an Integrated Psychological Interventions Combined With Ar_Rahman Listening for Reducing Psychological Distress and Enhancing Hope and Quality of Life Among Cancer Patients: A Randomized Controlled Trial
research

Psychological Distress (Depression, Anxiety and Stress) Cancer — supportive psychotherapy plus QURAN recitation9Surah Ar -Rahman

View on ClinicalTrials.gov
CT
Home-Based Randomized Trial of Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression
research

Treatment Resistant Depression (TRD), Major Depressive Disorder (MDD) — Spaced Transcranial Direct Current Stimulation (tDCS), Sham Spaced tDCS

View on ClinicalTrials.gov
CT
Effectiveness of a Mindfulness-Based Cognitive Behavioral Mobile Intervention for Misophonia
research

Misophonia, Misophonia Treatment — Mindfulness-Based Cognitive Behavioral Mobile Intervention

View on ClinicalTrials.gov
CT
Singula Phase 0.1 Primary Care Pilot
research

Depression - Major Depressive Disorder, Anxiety

View on ClinicalTrials.gov
CT
This Trial Corresponds to the Manuscript Titled: Effects of Tai Chi on Balance and Sleep Quality in Colorectal Cancer Patients Undergoing Chemotherapy
research

Colorectal Cancer — Tai Chi Exercise Program

View on ClinicalTrials.gov
CT
Clinical and Biological Correlates of Obsessive-Compulsive Disorder and Online Mindfulness-Based Cognitive Therapy
research

Obsessive - Compulsive Disorder — Mindfulness-based Cognitive Therapy for OCD

View on ClinicalTrials.gov
CT
Kinesiophobia, Physical Activity, Sleep, and Quality of Life in Women With Chronic Pelvic Pain
research

Chronic Pelvic Pain Syndrome (CPPS) — questionnaire

View on ClinicalTrials.gov
CT
Efficacy of Pre-cooling and Sweet-tasting Solution on Pain Related to Local Anesthesia Injection in Children
research

Dental Anesthesia, Sweet Taste Perception, Pain and Anxiety, Behavioral Management — Dental anesthesia

View on ClinicalTrials.gov
CT
Kinesiophobia, Postoperative Pain, and Early Mobilization After Elective Abdominal Surgery
research

Kinesiophobia — Tampa Scale for Kinesiophobia (TSK)

View on ClinicalTrials.gov
CT
State Representation in Early Psychosis 2
research

Early Psychosis, Psychosis, Schizophrenia, Bipolar Disorder With Psychosis, Schizoaffective Disorder

View on ClinicalTrials.gov
CT
Body Weight Changes After Switching to Lurasidone for Antipsychotic-induced Weight Gain in Bipolar Disorder: a Multicenter Retrospective Study of Selected Follow-up Cohort
research

Bipolar Disorder (BD) — Lurasidone

View on ClinicalTrials.gov
September 21, 2026
DEA
Schedules of Controlled Substances: Placement of Diphenidine in Schedule I
scheduling

With the issuance of this final rule, the Drug Enforcement Administration places the substance diphenidine (1-(1,2- diphenylethyl)piperidine), including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible, in sc

View on Federal Register
CT
Amygdala-Targeted Transcranial Temporal Interference Stimulation for Major Depressive Disorder: A Randomized Sham-Controlled Trial of Clinical Efficacy and Neurobiological Mechanisms
research

Major Depressive Disorder (MDD — Transcranial Temporal Interference Stimulation, Sham Transcranial Temporal Interference Stimulation

View on ClinicalTrials.gov
CT
Transforming Trauma Care
research

Post-Traumatic Stress Disorder (PTSD), Depression, Substance Use Disorder, Traumatic Injury — Trauma Resilience and Recovery Program Portal 2.0 (TRRP 2.0)

View on ClinicalTrials.gov
CT
Tai Chi Exercise to Improve Quality of Life and Depression in Elderly With Sarcopenia
research

Sarcopenia in Elderly — Tai Chi Exercise, Elderly exercise (senam lansia)

View on ClinicalTrials.gov
CT
Drawing and Writing Activities in Adolescents With Type 1 Diabetes
research

Type 1 Diabetes Mellitus (T1DM), Anxiety — Drawing and Writing Intervention

View on ClinicalTrials.gov
CT
Blood Flow Restriction Aerobic Exercise for Balance and Anxiety in Parkinson's Disease
research

Parkinson's Disease (PD), Anxiety, Postural Balance — Aerobic Exercise with Blood Flow Restriction, Aerobic Exercise without Blood Flow Restriction

View on ClinicalTrials.gov
CT
Virtual Reality-Based Breathing Exercise Before Angiography in Children
research

Anxiety, Angiocardiography — Virtual Reality-Based Guided Breathing Exercise

View on ClinicalTrials.gov
CT
Positive Affirmations and Preoperative Anxiety
research

Total Joint Replacement Surgery, Preoperative Anxiety — Guided imagery and positive affirmations

View on ClinicalTrials.gov
CT
Physiopathology of Behavioral Addictions and Biomarkers
research

Food Addiction, Sexual Addiction — blood sampling

View on ClinicalTrials.gov
CT
Attachment and Substance Use Disorder: An Interventional Study in an Addictology Day Hospital
research

Addiction Disorders — attachment-focused therapeutic program, psychoeducation-based intervention (standard care)

View on ClinicalTrials.gov
September 18, 2026
CT
Effects of Digital Detox on Mental Health in Young Adults
research

Anxiety Symptoms, Screen Time, Depressive Symptoms — App-based smartphone screen time restriction program

View on ClinicalTrials.gov
CT
Development of Low-Intensity Focused Ultrasound for Post Traumatic Brain Injury Depression
research

Post-traumatic Brain Injury Depression, Veteran Health — Active Low-Intensity Focused Ultrasound (LIFU), Sham Low-Intensity Focused Ultrasound (LIFU)

View on ClinicalTrials.gov
CT
Alexithymia, Pain Intensity, Quality of Life, and Psychological Symptoms in Chronic Coccydynia Patients Scheduled for Ganglion Impar Block
research

Coccydynia, Chronic Pain, Alexithymia — Psychometric and Clinical Survey Battery

View on ClinicalTrials.gov
CT
The Effect of the 4-7-8 Breathing Technique on Anxiety, Symptom Burden, and Sleep Quality During Chemotherapy
research

Chemotherapy — 4-7-8 breathing technique, routine care

View on ClinicalTrials.gov
CT
Effect of the Ansileve Supplement on the Well-being of Parents of Children Who Have Experienced a Medical Emergency: A Randomized Controlled Study
research

Parenting Anxiety, Child Hospitalization, Psychological Well-being — Ansileve SOS Spray, Ansileve

View on ClinicalTrials.gov
CT
Effect of Music on Dental Anxiety and Physiological Responses During Dental Drill and Suction Sounds
research

Dental Anxiety, Music Intervention — Music intervention

View on ClinicalTrials.gov
CT
The Effect of Using the Popit Toy and Stress Ball During Inhaler Therapy in Children
research

Non-Pharmacological Interventions, NEBULIZATION — Intervention 1 Popit toy, Intervention 2 Stress ball

View on ClinicalTrials.gov
CT
Assessment of Childbirth-Related Post-Traumatic Stress Disorder
research

Childbirth-related Post-traumatic Stress Disorder — City Birth Trauma Scale and Questionnaire on the assessment of healthcare utilization

View on ClinicalTrials.gov
September 17, 2026
CT
Lumateperone Added to Antidepressant Therapy in Adults With Major Depressive Disorder Experiencing Emotional Blunting
research

Blunted Emotion in Major Depressive Disorder — lumateparone 42 mg once daily, lumateparone

View on ClinicalTrials.gov
CT
Ketamine Treatment for Treatment-Resistant Depression - the Role of Framing
psychedelics · pharma · research

Treatment Resistant Depression (TRD) — Psychedelic framing, Biomedical framing

View on ClinicalTrials.gov
CT
Prevalence of Primary Headache in Multiple Sclerosis Patients
research

Multiple Sclerosis, Primary Headache Disorders, Migraine Disorders, Tension-Type Headache

View on ClinicalTrials.gov
CT
Deep Breathing Relaxation and Lemongrass Aromatherapy on Pain
research

Chronic Kidney Disease; End-Stage Renal Disease; Hemodialysis; Pain; Anxiety — Deep Breathing Relaxation, Lemongrass Aromatherapy

View on ClinicalTrials.gov
CT
Randomized Controlled Trial of Tirzepatide for Methamphetamine Use Disorder
research

Methamphetamine Use Disorder — Tirzepatide, Placebo (saline)

View on ClinicalTrials.gov
CT
Imaging Mitochondrial Complex-I in Alcohol Use Disorder
research

Alcohol Use Disorder (AUD), Healthy Controls Group - Age and Sex-matched — [F-18]BCPP-EF, [F-18]FDG

View on ClinicalTrials.gov
CT
Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent Mechanism
research

Alcohol Use Disorder (AUD), Alcohol Related Liver Disease — Endurance Exercise

View on ClinicalTrials.gov
September 16, 2026
CT
Brexanolone Lifting Outcomes Of Moms
research

Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression, Post-Natal Depression, Peripartum Depression — LPCN 1154A, Placebo

View on ClinicalTrials.gov
CT
A Migration-Focused Adaptation of EMDR for Psychological Distress Among Turkish Migrants
research

Depression, Anxiety, Stress, Social Adaptation — EMDR

View on ClinicalTrials.gov
CT
Longitudinal Effects of Brain Stimulation on Decision-Making and Reward Learning
research

Depression / Major Depressive Disorder

View on ClinicalTrials.gov
CT
The Effects of Trauma-informed Care Organization on Birth Professionals and Women's Experiences of Trauma.
research

Post-Traumatic Stress Disorder, Psychological Trauma — trauma-informed care training

View on ClinicalTrials.gov
September 15, 2026
CT
4-STEP Training Program for Social Media Addiction, Cognitive Fatigue, Psychological Distress, Academic Burnout and Procrastination Among Students
research

Social Media Addiction — 4-STEP-TPS

View on ClinicalTrials.gov
CT
A Study of the Correlation Between the Severity of Substance Use Disorder and the Intensity of Dependence on Generative Artificial Intelligence
research

Substance-related Disorders, Behavior, Addictive, Artificial Intelligence (AI) — Questionnaire assessment

View on ClinicalTrials.gov
CT
Breaking the Cycle of Social Media Addiction: Efficacy of a 4-STEP Training Program in Reducing Cognitive Fatigue, Psychological Distress, Academic Procrastination, and Burnout Among Adolescents
research

Social Media Addiction — 4-STEP-TPS

View on ClinicalTrials.gov
CT
Building a Computational Model of Auditory Hallucinations
research

Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature, Psychosis, SCHIZOPHRENIA 1 (Disorder), Schizophreni-form Disorder

View on ClinicalTrials.gov
September 14, 2026
DEA
Importer of Controlled Substances Application: Irvine Labs, Inc.
scheduling

Irvine Labs, Inc. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

View on Federal Register
DEA
Bulk Manufacturer of Controlled Substances Application: Cambrex High Point, Inc.
scheduling

Cambrex High Point, Inc. has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

View on Federal Register
CT
CHW-Enhanced Trauma Recovery
research

Traumatic Injury, Posttraumatic Stress Disorder, Depression, Social Determinants of Health — CHW support

View on ClinicalTrials.gov
CT
Screening and Monitoring of Mental Health in Educational Settings: Programme for Detection, Psychoeducation and Self-help
research

Anxiety, Depression Disorder, Bullying, Addiction, Suicide, Self Harm, Psychosis, Eating Disorders — program for the detection, referral, and psychoeducation in adolescents

View on ClinicalTrials.gov
CT
Effects of Nitraria Retusa Infusion on Clozapine-induced Metabolic Side Effects
research

Treatment Resistant Schizophrenia, Obesity & Overweight, Abdominal Obesity — The Nitraria retusa arm

View on ClinicalTrials.gov
CT
tACS for Self-Other Boundary in Schizophrenia
research

Schizophrenia / Schizoaffective Disorder — Transcranial Alternating Current Stimulation (tACS), Sham Transcranial Alternating Current Stimulation (tACS)

View on ClinicalTrials.gov
September 11, 2026
CT
Auricular Vagal Neuromodulation for Depression and Anxiety in Substance Use Disorder
research

Substance Use Disorder (SUD) — Transcutaneous Auricular Vagus Nerve Stimulation

View on ClinicalTrials.gov
CT
Endocannabinoids in Reward
cannabis · research

Cannabis Use Disorder — Dronabinol, Placebo

View on ClinicalTrials.gov
CT
Ultrasound Assessment of Gluteal Muscle in Patients Receiving Depot Antipsychotics and Healthy Volunteers
research

Psychotic Disorder, SCHIZOPHRENIA 1 (Disorder), Intramuscular Injection

View on ClinicalTrials.gov
CT
Phase I Trial of HHK101 in Patients With Schizophrenia
research

Schizophrenia — HHK101, HHK101, HHK101

View on ClinicalTrials.gov
September 10, 2026
CT
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
research

Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance — AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation

View on ClinicalTrials.gov
CT
Dexmedetomidine Combined With Transcutaneous Vagus Nerve Stimulation (taVNS) Can Reduce the Incidence of PTSD in Trauma Patients After Surgery
research

PTSD - Post Traumatic Stress Disorder, taVNS, Dexmedetomidine — Dexmedetomidine 0.1μg/kg/h, tavns

View on ClinicalTrials.gov
CT
Internet-Delivered Acceptance and Commitment Therapy (iACT) for Youth With PTSD and Chronic Pain
research

Chronic Pain, PTSD — iACT

View on ClinicalTrials.gov
CT
Social Media Withdrawal in Pregnancy: Effects on Maternal Mental Health and Misinformation
research

Pregnancy — Brick device

View on ClinicalTrials.gov
CT
Mobile Application-Based Interventions for Cannabis Use in Young Adults With First Episode Psychosis
cannabis · research

First Episode Psychosis (FEP), Psychosis, Schizophreni-form Disorder, Dependence Addictive — CHAMPS, I Can Change

View on ClinicalTrials.gov
CT
Modulating Neural Mechanisms of Reward Processing in Tobacco Users
research

Tobacco Use Disorder — PRIME TMS, Standard TMS

View on ClinicalTrials.gov
September 9, 2026
CT
Pilot Testing of the emPath Platform to Improve Medication for Opioid Use Disorder (MOUD) Linkage and Retention Among Adults With Opioid Use Disorder in Durham, North Carolina
digital · research

Opioid Use Disorder, Digital Health Intervention, Telemedicine, Outreach Intervention — emPath Intervention

View on ClinicalTrials.gov
CT
Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment
research

Cigarette Smoking, Veterans — Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling

View on ClinicalTrials.gov
CT
Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized Patients
research

Alcohol Withdrawal, Alcohol Abstinence, Alcohol Use Disorder — Sodium Acetate, Placebo

View on ClinicalTrials.gov
CT
The BAARD Study : Evaluating a Computerized Approach to Treatment Selection in Older Adults With Treatment Resistant Depression.
research

Late Life Treatment Resistant Depression, Depression - Major Depressive Disorder, Treatment Resistant Depression — Aripiprazole Augmentation, Bupropion Augmentation

View on ClinicalTrials.gov
September 8, 2026
DEA
Bulk Manufacturer of Controlled Substances Application: Irvine Labs, Inc.
scheduling

Irvine Labs, Inc. has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

View on Federal Register
DEA
Importer of Controlled Substances Application: Fisher Clinical Services, Inc.
scheduling

Fisher Clinical Services, Inc. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

View on Federal Register
DEA
Importer of Controlled Substances Application: Cambrex High Point, Inc.
scheduling

Cambrex High Point, Inc. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

View on Federal Register
DEA
Importer of Controlled Substances Application: Fresenius Kabi USA, LLC
scheduling

Fresenius Kabi USA, LLC has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

View on Federal Register
DEA
Importer of Controlled Substances Application: AndersonBrecon, Inc DBA PCI Pharma Services
scheduling

AndersonBrecon, Inc DBA PCI Pharma Services has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

View on Federal Register
CT
Group Cognitive-Behavioral Intervention for Problematic Internet Use in Nepalese University Students
research

Problematic Internet Use, Internet Addiction — Group Cognitive-Behavioral Intervention for Problematic Internet Use

View on ClinicalTrials.gov
CT
HD-tACS for Alcohol Use Disorder
research

Alcohol Use Disorder — HD-tACS, Sham HD-tACS

View on ClinicalTrials.gov
CT
A Relation Between Craving Induction and Treatment Response in Deep Transcranial Magnetic Stimulation (dTMS) for Reducing Antipsychotic-induced Weight Gain in Schizophrenia
research

Schizophrenia, Antipsychotic Induced Weight Gain — Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Active, Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Sham

View on ClinicalTrials.gov
CT
Efficacy and Safety of Individualized Sequential Accelerated Theta Burst Stimulation in Improving Cognitive Function in Schizophrenia
research

Schizophrenia / Schizoaffective Disorder, TMS, Cognitive, PET / MR — Sequential Dual-Site Accelerated Theta Burst Stimulation (SD-aTBS), Sham Sequential Dual-Site Accelerated Theta Burst Stimulation

View on ClinicalTrials.gov
CT
Broadband Near Infrared Spectroscopy to Understand the Role of Brain Cytochrome C Oxidase in Bipolar Disorder
research

Bipolar Disorder Depression — Lurasidone (Latuda)

View on ClinicalTrials.gov
September 4, 2026
CT
Project SHIELD 2.0: Police Education to Support Public Health in Kentucky
research

HIV, Substance Use Disorder (SUD) — SHIELD 2.0

View on ClinicalTrials.gov
CT
Comparison of Efficacy of Minocyclin and Celecoxib as Adjunctive Treatment in Treatment Resistant Cases of Major Depressive Disorder
research

Major Depressive Disorder (MDD), Treatment-resistant Depression (TRD) — Minocycline, Celecoxib

View on ClinicalTrials.gov
CT
Bipolar RFA Versus Phenol Neurolysis for Knee Osteoarthritis Pain
research

Gonarthrosis — Phenol Chemical Neurolysis, Ultrasound-Guided Bipolar Radiofrequency Ablation

View on ClinicalTrials.gov
September 3, 2026
CT
Discontinuing Psychotropic Medication Before Psychotherapy for PTSD
research

Post-traumatic Stress Disorder (PTSD)

View on ClinicalTrials.gov
CT
Comparative Efficacy of Cognitive Behavioral and Mindfulness Therapies in Reducing Post-Traumatic Stress Disorder Among Interpersonal Violence Survivors
research

Post-traumatic Stress Disorder (PTSD), Post-Traumatic Stress Disorder — Cognitive Behavioral Therapy (CBT), Mindfulness-Based Therapy (MBT), Psychoeducation

View on ClinicalTrials.gov
CT
Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum
research

Depression, Anxiety, Addiction, Emotion, Craving, Stress

View on ClinicalTrials.gov
CT
Lemborexant for Cannabis Use Disorder
cannabis · research

Cannabis Use Disorder — Lemborexant 10mg, Placebo, Brief Behavioural Intervention

View on ClinicalTrials.gov
CT
Behavioural Activation Therapy and Ketamine for Treatment-Resistant Depression
pharma · research

Treatment Resistant Depression, Major Depressive Disorder (MDD) — Ketamine (0.5 mg/kg), Behavioural Activation Therapy

View on ClinicalTrials.gov
CT
A Prospective, Observational, Single-Arm, Multicenter Real-World Study Evaluating the Treatment Pattern, Safety and Effectiveness of Xanomeline and Trospium Chloride Capsules (KarXT) in the Treatment of Chinese Adult Participants With Schizophrenia
research

Schizophrenia Disorder — Xanomeline and trospium chloride (KarXT)

View on ClinicalTrials.gov
September 2, 2026
CT
Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use Disorder
research

Opioid Use Disorder, OAT — [11C]OMAR

View on ClinicalTrials.gov
September 1, 2026
CT
Frequency- and Intensity-Dependent After-Effects of High-Definition Transcranial Alternating Current Stimulation on Resting-State Electroencephalography
research

Schizophrenia With Auditory Hallucinations — high-definition transcranial alternating current stimulation(HD-tACS), sham high-definition transcranial alternating current stimulation(HD-tACS)

View on ClinicalTrials.gov
August 31, 2026
FDA
Rahim Shafa; Denial of Hearing; Final Debarment Order
scheduling

The Food and Drug Administration (FDA or Agency) is denying a request for a hearing submitted by Rahim Shafa (Dr. Shafa) and is issuing an order under the Federal Food, Drug, and Cosmetic Act (FD&C Act) permanently debarring Dr. Shafa from providing services in any capacity to a

View on Federal Register
CT
Symptom Assessment in Adolescents Placed on Child Welfare
research

Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD

View on ClinicalTrials.gov
CT
The ConCERN Intervention for Loved Ones of Those With Opioid Use Disorder
research

Opioid Use Disorder — ConCERN intervention, Treatment as Usual

View on ClinicalTrials.gov
CT
The Safety and Effectiveness of dTMS for Reducing Antipsychotic-induced Weight Gain
research

Schizophrenia Spectrum, Schizophrenia, Antipsychotic Induced Weight Gain — dTMS of accelerated intermittent theta burst stimulation, ACC-iTBS, Sham stimulation

View on ClinicalTrials.gov
August 28, 2026
CT
Psilocybin-Assisted Psychotherapy for Veterans With PTSD
psychedelics · research

Posttraumatic Stress Disorder (PTSD) — Psilocybin-assisted Psychotherapy

View on ClinicalTrials.gov
CT
Women Who Are Victims of Violence: Treatment of PTSD Through Reactivation of Traumatic Memories Using Propranolol
research

Post-Traumatic Stress Disorder, PTSD — Propranolol, Psychotherapy

View on ClinicalTrials.gov
CT
Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 3
research

Opioid Abuse (Disorder), Clinical Decision Support — Refined EMBED CDS, Provider alert that nurse completed COWS

View on ClinicalTrials.gov
August 27, 2026
DEA
Schedules of Controlled Substances: Placement of Cipepofol in Schedule IV
scheduling

On May 29, 2026, the United States Food and Drug Administration (FDA) approved a new drug application for Cypsedo (cipepofol) for induction of general anesthesia in adults undergoing surgery. The Department of Health and Human Services provided the Drug Enforcement Administration

View on Federal Register
DEA
Schedules of Controlled Substances: Temporary Placement of 5,6-Dichloro Brorphine, 5,6-Dichloro Desmethylchlorphine, N-Propionitrile Chlorphine, and Spirochlorphine in Schedule I of the Controlled Substances Act
scheduling

The Drug Enforcement Administration (DEA) issues this temporary order to schedule 1-(1-(1-(4-bromophenyl)ethyl)piperidin-4- yl)-5,6-dichloro-1,3-dihydro-2H-benzo[d]imidazol-2-one (commonly known as 5,6-dichloro brorphine or SR-14968); 5,6-dichloro-1-(1-(4- chlorobenzyl)piperidin-

View on Federal Register
CT
Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking
research

Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation, Community Health Workers, Cardiovascular (CV) Risk, Tobacco Use Disorder — Integrated CHW Support intervention, Enhanced usual care (EUC)

View on ClinicalTrials.gov
CT
Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation
research

Smoking Cessation, Cigarette Smoking, Tobacco Use, Nicotine Dependence — Mindful Smoking and Sensor-Band Intervention, Smoking Cessation Information

View on ClinicalTrials.gov
CT
Dissecting Immunological and Autoimmune Mechanisms of Neuropsychiatric Diseases
research

Neuropsychiatric Symptom

View on ClinicalTrials.gov
CT
Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain
research

Bipolar Radiofrequency Ablation, Unipolar Radiofrequency Ablation, Knee Osteoarthritis, Pain — Unipolar radiofrequency ablation, Bipolar radiofrequency ablation

View on ClinicalTrials.gov
August 26, 2026
DEA
Schedules of Controlled Substances: Temporary Placement of Mitragynine Pseudoindoxyl, MGM-15, and MGM-16 in Schedule I
scheduling

The Drug Enforcement Administration (DEA) is issuing this temporary order to schedule three 7-hydroxymitragynine-related substances (mitragynine pseudoindoxyl, MGM-15, and MGM-16), including their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, whenever

View on Federal Register
DEA
Importer of Controlled Substances Application: Curia New York Inc.
scheduling

Curia New York Inc. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

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DEA
Bulk Manufacturer of Controlled Substances Application: Cambrex Charles City
scheduling

Cambrex Charles City has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

View on Federal Register
DEA
Bulk Manufacturer of Controlled Substances Application: Chemtos, LLC
scheduling

Chemtos, LLC has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

View on Federal Register
DEA
Importer of Controlled Substances Application: Experic LLC
scheduling

Experic LLC has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

View on Federal Register
DEA
Importer of Controlled Substances Application: Cambrex Charles City
scheduling

Cambrex Charles City has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

View on Federal Register
FDA
International Drug Scheduling; Single Convention on Narcotic Drugs; Convention on Psychotropic Substances; Clobromazolam (Phenazolam); Cychlorphine (N-Propionitrile Chlorphine); Desalkylgidazepam (Bromonordiazepam); Ethylbromazolam; Etomethazene (5-Methyl Etodesnitazene); Spirochlorphine (R6980); Etomidate; Medetomidine; Request for Comments
scheduling

The Food and Drug Administration (FDA or Agency) is providing interested persons with the opportunity to submit comments concerning abuse potential, actual abuse, medical usefulness, trafficking, and impact of scheduling changes on availability for medical use of eight drug subst

View on Federal Register
CT
téléwork and Consumer Behavior: Longitudinal Study
research

Addictions — data collection

View on ClinicalTrials.gov
CT
Supporting Treatment for Opioids and Recovery Capital (STORC) - R61 Phase
research

Opioid Use Disorder — STORC

View on ClinicalTrials.gov
CT
Sensory and Physical Reactions to Beverage Cues
research

Alcohol Use Disorder (AUD) — Alcohol Cue Reactivity Paradigm

View on ClinicalTrials.gov
CT
Accelerated Neuromodulation Therapy and Neurocomputational Biomarkers in Individuals at Clinical High Risk for Psychosis
research

Clinical High Risk for Psychosis (CHR), Psychotic Disorders, Prodromal Symptoms — Active Intermittent Theta Burst Stimulation (BEAM-F3 Targeting), Sham Comparator: Sham iTBS

View on ClinicalTrials.gov
CT
NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in Schizophrenia
research

Schizophrenia, Schizoaffective Disorder, Cognitive Impairment, Visual Impairment — Perceptual Discrimination Training, Cognitive Control Training

View on ClinicalTrials.gov
August 25, 2026
CT
Individualized (fMRI-guided) TMS Intervention for Post-Traumatic Stress Disorder (PTSD)
research

PTSD, Post Traumatic Stress Disorder (PTSD) — Active Transcranial Magnetic Stimulation (TMS), Sham Transcranial Magnetic Stimulation (TMS)

View on ClinicalTrials.gov
CT
Varenicline as a Treatment for Cannabis Use Disorder
cannabis · research

Cannabis Abuse — Varenicline (Chantix), Placebo

View on ClinicalTrials.gov
CT
Precision Closed-loop Brain-Computer Interface Neuromodulation for Treatment-Resistant Depression
research

Treatment-Resistant Major Depressive Disorder, Major Depressive Disorder — Closed-loop Deep Brain Stimulation (DBS), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)

View on ClinicalTrials.gov
CT
Chemokine Receptors on CD8+ T Cells in Patients With Bipolar Disorder
research

Bipolar Affective Disorders — CD8+ T-Cell Gene Expression Analysis

View on ClinicalTrials.gov
CT
Identifying Biomarkers of Response to Digital Interventions for Mood Disorders
research

Depression / Major Depressive Disorder, Bipolar Disorder (BD) — Online Cognitive Behavioural Therapy

View on ClinicalTrials.gov
August 24, 2026
CT
Written Exposure in Substance Treatment (WEST 3.0): Randomized Controlled Trial
research

Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD) — Written Exposure Therapy, Treatment as Usual

View on ClinicalTrials.gov
CT
Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders
research

Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders, Occupational Stress, Emotional Regulation Difficulties, Anger Problems, Relational Problems, Irritability — Brazilian Jiu-Jitsu Program

View on ClinicalTrials.gov
CT
Long-Term Real-World Safety of Cobenfy in Adults With Schizophrenia
research

Schizophrenia — xanomeline-trospium chloride, Oral antipsychotics

View on ClinicalTrials.gov
CT
Improving Quality of Informal Care for People With Schizophrenia
research

Schizophrenia — Dyadic Multicomponent Intervention (DMI), Dyadic Benefit-Finding Intervention (DBFI)

View on ClinicalTrials.gov
CT
Effectiveness of a Board Game Intervention on Cognitive and Functional Outcomes in Older Adults With Schizophrenia
research

Schizophrenia — Scaffolding-Based Board Game Intervention

View on ClinicalTrials.gov
CT
40-Hz Audiovisual Stimulation in Schizophrenia Spectrum Disorders
research

Anxiety — 40-Hz Binaural Beat Music Combined With 40-Hz Rhythmic Photic Stimulation, Sham group

View on ClinicalTrials.gov